Soolantra (ivermectin) Cream Approved for Rosacea Treatment

By: Vivacare - Dr. Mark Becker

Saturday, December 27th

Soolantra rosacea treatmentSoolantra Cream (1% ivermectin) is a new rosacea medicationa approved by the US FDA for the treatment of the bumps and pimples associated with type 2 rosacea (papulopustular rosacea). This medication is formulated for once-daily use.

How Soolantra Cream works to lessen the symptoms of rosacea is not clearly understood. However, ivermectin, the active ingredient in Soolantra Cream, has both anti-inflammatory that may reduce localize skin swelling and antiparasitic activity that may help kill the Demodex mite found on the skin. Studies showing ivermectin’s clinical benefits for the treatment of rosacea support theories that infestation with the Demodex mite may be responsible for some of the signs associated with rosacea. These Demodex mites appear in normal skin, but they may be found in greater numbers on the faces of those with rosacea.

The approval of Soolantra Cream was based on two  Phase III randomized, double-blind studies. The benefits of treatment were observed as early as the second week of treatment with continuous improvement with longer use. Soolantra Cream was found safe and well-tolerated for up to 52 weeks in total, which is important for rosacea patients who often have sensitive skin.

In addition, a separate head-to-head study that compared Soolantra to metronidazole 0.75% cream (the current gold standard treatment), Soolantra Cream was shown to be more efficacious from as early as week three onward.

Some minor side effects were reported, including skin burning sensation and skin irritation.

About Rosacea

Rosacea is a chronic skin condition that causes redness and swelling of the face that can also affect the scalp, neck, ears, chest, and back. Eye symptoms (ocular rosacea) are also reported by half of people with rosacea.

Those afflicted with rosacea may first notice a tendency to flush or blush easily (facial flushing). The condition progresses to persistent redness, pimples, and visible, threadlike blood vessels (telangiectasias) in the center of the face. These skin changes can eventually spread to the cheeks, forehead, chin, and nose.

Rosacea occurs most commonly in people 30 to 50 years of age. Although women have rosacea more commonly than men, men tend to suffer more severe forms.